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Quality Assurance/Data Integrity Manager - Community …
WebJan 10, 2024 · About HMPL-760. HMPL-760 is an investigational, highly selective, non-covalent, third-generation inhibitor of BTK, both wild-type and C481S mutant enzymes, with pre-clinical data suggesting high target specificity and higher potency versus first … WebApr 11, 2024 · The poster outlined preclinical data showing HMPL-760 is a reversible, selective, highly potent BTK inhibitor targeting both BTK WT and BTK C481S. The first-in-human Phase I clinical trials of HMPL-760 are under way in patients with relapsed/refractory B-Cell Non-Hodgkin’s Lymphoma (NCT05190068). WebFeb 2, 2015 · Determining APOR-Ceiling for HOEPA Test? 12/09/2013. Beginning in January 2014 we will need to check our HELOC loans for HOEPA coverage. We use the one year treasury as an index (currently .125%) with a 2.75% margin, floor of 5% & ceiling of 12%. The rate is subject to change monthly. selectivicat